By Pekka Lappalainen
This publication presents a complete view on actin monomer-binding proteins and the mechanisms in which they give a contribution to actin dynamics and numerous actin-dependent mobile approaches. This new identify includes chapters that describe the elemental mechanisms of actin dynamics in addition to the structural rules wherein a variety of actin-binding proteins engage with actin. The publication is acceptable extra analyzing for college students in complex telephone biology classes.
Read or Download Actin-Monomer-Binding Proteins PDF
Best molecular biology books
This quantity offers the 1st finished remedy of the wide variety of makes use of for Xenopus laevis oocytes and embryos in phone and molecular biology. each one bankruptcy contains heritage info, experimental protocols, and instructed purposes. an intensive array of thoughts is featured. The authors are skilled researchers who've written chapters that may be precious to either skilled researchers and to these new to Xenopus as an experimental approach.
The crucial Dogma -- DNA and RNA -- Chromosomes -- Proteins -- The imperative Dogma -- Transcription and Translation in Perl -- RNA Secondary constitution -- Messenger and Catalytic RNA -- degrees of RNA constitution -- Constraints on Secondary constitution -- RNA Secondary constructions in Perl -- Counting Hydrogen Bonds -- Folding RNA -- evaluating DNA Sequences -- DNA Sequencing and series meeting -- Alignments and Similarity -- Alignment and Similarity in Perl -- Predicting Species: Statistical types -- Perl Subroutine Libraries -- Species Prediction in Perl -- Substitution Matrices for Amino Acids -- extra on Homology -- Deriving Substitution Matrices from Alignments -- Substitution Matrices in Perl -- The PAM Matrices -- PAM Matrices in Perl -- series Databases -- FASTA layout -- GenBank layout -- GenBank's characteristic destinations -- interpreting series documents in Perl -- Object-Oriented Programming in Perl -- The SimpleReader type -- Hiding dossier codecs with strategy Inheritance -- neighborhood Alignment and the BLAST Heuristic -- The Smith-Waterman set of rules -- The BLAST Heuristic -- Preprocessing the question String -- Scanning the objective String -- imposing BLAST in Perl -- facts of BLAST Database Searches -- BLAST rankings for Random DNA -- BLAST ratings for Random Residues -- BLAST records in Perl -- examining BLAST Output -- a number of series Alignment I -- Extending the Needleman-Wunsch set of rules -- NP-Completeness -- Alignment Merging: A development Block for Heuristics -- Merging Alignments in Perl -- discovering an outstanding Merge Order
Sorting and Recycling Endosomes offers the most recent details on endosomes, the receiving compartment for endocytosed cargos, and the donor compartment and sorting station for cargos specific to lysosomes, Golgi, or plasma membrane. lately, the significance of endosomes as a sorting and recycling compartment has develop into more and more liked.
Biochemistry of Collagens, Laminins, and Elastin: constitution, functionality, and Biomarkers offers a finished creation to collagen and structural proteins. style I collagen is likely one of the such a lot considerable molecules within the physique, enjoying crucial roles in numerous tissues, really bone and epidermis.
- Physics and Biology
- Protein \3- DNA Interactions
- Proteoglycans: Structure, Biology and Molecular Interactions
- Regulation of Organelle and Cell Compartment Signaling: Cell Signaling Collection
- Genes in Conflict: The Biology of Selfish Genetic Elements
Additional info for Actin-Monomer-Binding Proteins
58. Blanchoin L, Robinson RC, Choe S et al. Phosphorylation of Acanthamoeba actophorin (ADF/cofilin) blocks interaction with actin without a change in atomic structure. J Mol Biol 2000; 295(2):203-211. 59. Smertenko AP, Jiang CJ, Simmons NJ et al. Ser6 in the maize actin-depolymerizing factor, Z m A D F 3 , is phosphorylated by a calcium-stimulated protein kinase and is essential for the control of functional activity. Plant J 1998; 14(2):187-193. 60. Arber S, Barbayannis FA, Hanser H et al. Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase.
D e t e c t i o n of a sequence involved in a c t i n - b i n d i n g a n d phosphoinositide-binding in the N-terminal side of cofilin. Mol Cell Biochem 1999; 190(1-2): 133-141. 90. Yonezawa N , Nishida E, lida K et al. Inhibition of the interactions of cofilin, destrin, and deoxyribonuclease I with actin by phosphoinositides. J Biol Chem 1990; 265(15):8382-8386. 91. Yonezawa N , Nishida E, lida K et al. Inhibition of actin polymerization by a synthetic dodecapeptide patterned on the sequence a r o u n d the a c t i n - b i n d i n g site of cofilin.
Dawe HR, Minamide LS, Bamburg JR et al. ADF/Cofilin controls cell polarity during fibroblast migration. Curr Biol 2003; 13(3):252-257. 130. Nishita M, Tomizawa C, Yamamoto M et al. Spatial and temporal regulation of cofilin activity by LIM kinase and Slingshot is critical for directional cell migration. J Cell Biol 2005; 171(2):349-359. 131. Gehler S, Shaw AE, Sarmiere PD et al. Brain-derived neurotrophic factor regulation of retinal growth cone filopodial dynamics is mediated through actin depolymerizing factor/cofilin.