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By A. Chadwick Cox (auth.), Thomas Briggs Ph.D., Albert M. Chandler Ph.D. (eds.)

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A B. C. D. E. Glucose can be synthesized from non-carbohydrate precursors. Gluconeogenesis is not a reversal of glycolysis. Gluconeogenesis and glycolysis are reciprocally regulated. Lactate and alanine formed by contracting muscle are converted into glucose in muscle. Six high energy phosphate bonds are spent in synthesizing one molecule of glucose from pyruvate. 7. Which one of the following statements is NOT characteristic of gluconeogenesis? A It does not require energy in the form of ATP. B.

An answer may be used one or more times, or not at all. Questions 28-31: Blood levels of enzymes found intracellulariy in various organs are used as indicators of organ damage. For each disease named in Questions 28-31, select the lettered enzyme with which it is most closely associated. A B. C. D. E. F. G. H. Glutamic-oxaloacetic transaminase Glutamic-pyruvic transaminase Alkaline phosphatase Acid phosphatase Sorbitol dehydrogenase Ornithine transcarbamoylase Ornithine decarboxylase Glucose-6-phosphate dehydrogenase 28.

5x10- 4 M 6x10- 4 M 16. The effect of pH on an enzyme-catalyzed reaction reflects: A increased rate of forward reaction B. increased rate of reverse reaction C. decreased activation energy for forward reaction D. decreased activation energy for reverse reaction E. ionization of the enzyme. 17. Conversion of zymogen to the active enzyme involves: A B. C. D. E. phosphorylation methylation dimer formation cleavage of one or more specific peptide bonds disulfide bond formation. - 29 18. In catalyzing a reaction, an enzyme: 23.

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