Download Biofabrication. Micro- and Nano-fabrication, Printing, by Gabor Forgacs, Wei Sun PDF

By Gabor Forgacs, Wei Sun

Biofabrication is a realistic advisor to the unconventional, inherently cross-disciplinary medical box that makes a speciality of biomanufacturing techniques and a similar diversity of rising applied sciences. those strategies and applied sciences eventually additional the advance of goods that can contain residing (cells and/or tissues) and nonliving (bio-supportive proteins, scaffolds) parts. The ebook introduces readers to phone printing, patterning, assembling, 3D scaffold fabrication, cell/tissue-on-chips as a coherent micro-/nano-fabrication toolkit. Real-world examples illustrate find out how to observe biofabrication suggestions in components equivalent to regenerative medication, prescribed drugs and tissue engineering.

In addition to being an important reference for scientists, engineers and technicians trying to practice biofabrication recommendations, this booklet additionally offers an perception into destiny advancements within the box, and power new functions.

  • Discover the multi-disciplinary toolkit supplied by means of biofabrication and use it on boost new items, thoughts and therapies
  • Covers a variety of vital rising applied sciences in a coherent demeanour: mobilephone printing, patterning, assembling, 3D scaffold fabrication, cell/tissue-on-chips...
  • Readers boost the power to use biofabrication applied sciences via sensible examples

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Additional info for Biofabrication. Micro- and Nano-fabrication, Printing, Patterning and Assemblies

Example text

Tissue Eng 2010;16:2369À79. [12] Finger AR, Sargent CY, Dulaney KO, Bernacki SH, Loboa EG. Differential effects on messenger ribonucleic acid expression by bone marrow-derived human mesenchymal stem cells seeded in agarose constructs due to ramped and steady applications of cyclic hydrostatic pressure. Tissue Eng 2007;13:1151À8. [13] Ashton RS, Banerjee A, Punyani S, Schaffer DV, Kane RS. Scaffolds based on degradable alginate hydrogels and poly(lactide-co-glycolide) microspheres for stem cell culture.

There have been a few attempts to use a decellularized whole organ for transplant. Uygun et al. [56] demonstrated an approach to generate transplantable liver grafts using decellularized liver matrix. In another study, Ott et al. 2). 2 Porous scaffolds with irregular pores Porous 3D scaffolds play an imperative role in tissue engineering by controlling cell function and guiding new organ formation. 3 Application of 3D tissue scaffolds scaffolds have been developed for tissue engineering of liver, bladder, nerve, skin, bone, cartilage, ligament, and so on [58].

References [3] Melchels FPW, Domingos MAN, Klein TJ, Malda J, Bartolo PJ, et al. Additive manufacturing of tissues and organs. Prog Polym Sci 2011. [In Press]. [4] Sun H, Qu Z, Guo Y, Zang G, Yang B. In vitro and in vivo effects of rat kidney vascular endothelial cells on osteogenesis of rat bone marrow mesenchymal stem cells growing on polylactide-glycolic acid (PLGA) scaffolds. Biomed Eng Online 2007;6:41. [5] Sabir M, Xu X, Li L. A review on biodegradable polymeric materials for bone tissue engineering applications.

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