Download Computational Approaches in Chlamydomonas reinhardtii for by Pratyoosh Shukla, M.V.K. Karthik PDF

By Pratyoosh Shukla, M.V.K. Karthik

This booklet describes the feasibility of utilizing molecular dynamics as a screening strategy to determine the soundness of HydA1 and PetF interactions. Structure-based computational techniques are essential to realize and signify protein-protein complexes and their services. It introduces the concept for particular proteins, homology modeling is the simplest procedure and that docking algorithms are an more and more robust instrument for offering an in depth rationalization of such interactions. This publication is an invaluable resource of knowledge on biomass-based biofuels for researchers within the box of bio-hydrogen and bioinformatics ideas. Biofuel and bioenergy made out of unicellular microalgae Chlamydomonas reinhardtii is a fresh power resource and supplying information regarding practical optimization in HydA1 and PetF interactions can assist researchers to undertake quick screening easy methods to determine key protein complexes and their features. The ebook additionally presents an advent to hydrogenases and linked Chlamydomonas reinhardtii, that is an invaluable version microorganism for study on biofuel creation. The ebook makes a speciality of the in silico equipment similar to phylogenetic reports, homology modeling, molecular docking, electrostatic experiences and conformational research, that have the aptitude to turn into the main cost effective tools for bio-fuel production.

This e-book offers a helpful source to senior undergraduate and graduate scholars, researchers, pros and different participants or teams operating within the sector of bioenergy with distinct connection with microalgal biofuel.

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Extra info for Computational Approaches in Chlamydomonas reinhardtii for Effectual Bio-hydrogen Production

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3 Conformational analysis of HydA1 model elucidates that there is slight shift in secondary structure due to binding. The affected amino acids are Leu119, Glu141 and Gly142 where they change from coil to extended conformations as shown in Figs. 6. Interestingly it was noticed that these amino acids are missing in binding site of HydA1 but their structural modifications allows hyda1 to bind petf with more stability. Finally, through Consurf studies we have proved that amino acids (Leu119, Glu141 and Gly142) undergoing conformational change and those present in binding site viz.

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K. 1007/978-81-322-2383-2 31 32 References Crabtree GW et al (2008) The hydrogen fuel alternative. ETATS-UNIS, Materials Research Society, Warrendale Dent RM, Han M, Niyogi KK (2001) Functional genomics of plant photosynthesis in the fast lane using Chlamydomonas reinhardtii. Trends Plant Sci 6:364–371 Ducat DC, Way JC, Silver PA (2011) Engineering cyanobacteria to generate high-value products. Trends Biotechnol 29(2):95–103 Elowitz MB, Leibler S (2000) A synthetic oscillatory network of transcriptional regulators.

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