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3). From an ergogenic viewpoint, resynthesis of PCr could be the critical factor during sustained very high intensity exercise.  Modified from Podium Kreatin.  There PCr regenerates ATP from the ADP formed during contraction. Dietary creatine intake accounts for about half of the body's daily need for creatine, with the remainder obtained through endogenous creatine synthesis from the amino acids glycine, arginine, and methionine.  First, PCr serves as a cellular buffer through the following reaction: Phosphocreatine may serve as a cellular buffer through the following reaction: It has been proposed that one of the primary functions of the phosphagen system is to buffer elevations in ADP rather than to simply resynthesize ATP— a possible means to prevent premature fatigue.

Also, some endurance athletes may use PCr during intensive exercise periods within an athletic contest and may benefit from enhanced PCr resynthesis during aerobic recovery periods.  Enhancing training Increased creatine or PCr may enable athletes to reach a higher training load, improve repetitive­interval sprint capacity, reduce training fatigue, and possibly accelerate muscle hypertrophy—all factors that may enhance competitive performance.  Increasing body mass An increased fat­free body weight, or muscle mass, might be advantageous in sports requiring a high absolute power output to resist the inertia of another body or to overcome an external object.

From an ergogenic viewpoint, resynthesis of PCr could be the critical factor during sustained very high intensity exercise.  Modified from Podium Kreatin.  There PCr regenerates ATP from the ADP formed during contraction. Dietary creatine intake accounts for about half of the body's daily need for creatine, with the remainder obtained through endogenous creatine synthesis from the amino acids glycine, arginine, and methionine.  First, PCr serves as a cellular buffer through the following reaction: Phosphocreatine may serve as a cellular buffer through the following reaction: It has been proposed that one of the primary functions of the phosphagen system is to buffer elevations in ADP rather than to simply resynthesize ATP— a possible means to prevent premature fatigue.

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