By Peter R. Shewry, Arthur S. Tatham, Allen J. Bailey
Elastic proteins ensue in a variety of organic platforms the place they've got advanced to satisfy unique organic roles. the easiest identified contain proteins in vertebrate muscle mass and connective tissues, comparable to titin, elastin, fibrillin and spider silks. curiosity in elastomeric proteins is at present excessive for a number of purposes. to begin with, they've got organic and clinical value, really in human ailment. Secondly, the weird houses of proteins similar to spider silks offer possibilities to boost novel fabrics. Thirdly, the improvement of scanning probe microscopy makes it attainable to check constructions and biomechanical houses of those proteins on the unmarried molecule point.
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Additional resources for Elastomeric Proteins: Structures, Biomechanical Properties, and Biological Roles
Biol. 199, 2745–55. Davis, E. C. (1993) Stability of elastin in the developing mouse aorta – A quantitative autoradiographic study. Histochemistry 100, 17–26. Denny, M. (1976) The physical properties of spider’s silk and their role in the design of orb-webs. J. Exp. Biol. 65, 483–506. Gordon, J. E. (1988) The Science of Structures and Materials. New York, NY: Scientiﬁc American Library, 217 pp. Gosline, J. M. (1980) The elastic properties of rubber-like proteins and highly extensible tissues. In: Mechanical Properties of Biological Materials, J.
Alexander, R. , and Vernon, A. (1975) Mechanics of hopping by kangaroos (Macropodidae). J. Zool. 177, 265–303. Bennet-Clark, H. C. (1975) The energetics of the jump of the locust Schistocerca gregaria. J. Exp. Biol. 63, 53–83. Bennet-Clark, H. C. (1997) Tymbal mechanics and the control of song frequency in the cicada Cyclochila australasiae. J. Exp. Biol. 200, 1681–94. Bennet-Clark, H. , and Lucey, E. C. A. (1967) The jump of the ﬂea: A study of the energetics and a model of the mechanism. J. Exp.
2). As water content and temperature are lowered and strain rate increased, elastin enters its glass transition (zone 2). Here, it exhibits higher stiffness and extensibility, but lower resilience, leading to a toughness that is at least an order of magnitude higher. It is worth noting that, because elastin must be dehydrated or cooled to exhibit zone 2 behaviour at moderate strain rates, it may never function in this region of its viscoelastic curve under natural conditions. However, mussel byssal ﬁbres achieve similar toughness levels when fully hydrated in seawater, and so it may be fruitful to discover the molecular origins of this enhanced toughness.