By Horst Urbach
MRI can play an enormous position in deciding upon and localizing epileptogenic foci. This e-book goals to supply the scientific and imaging details required so as to make a decision no matter if an MRI experiment is suitable and if it is prone to be adequate to become aware of a lesion. the 1st a part of the publication offers heritage info on epilepsy sufferers and explains the way to practice an MRI exam. exact realization is paid to practical MRI and post-processing, and the exam of subcategories of sufferers can be mentioned. the second one a part of the booklet then files the MRI findings acquired within the complete variety of epileptogenic lesions using top of the range photos. all through, emphasis is put on guiding the reader within the right interpretation of the imaging findings. either radiologists and referring physicians will locate this e-book to be an necessary advisor to the optimum use of MRI in epilepsy.
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Extra resources for MRI in Epilepsy
1016/S0140-6736(98)03543-0 Olafsson E, Ludvigsson P, Gudmundsson G, Hesdorffer D, Kjartansson O, Hauser WA (2005) Incidence of unprovoked seizures and epilepsy in Iceland and assessment of the epilepsy syndrome classification: a prospective study. Lancet Neurol 4(10):627–634. 1016/ S1474-4422(05)70172-1 Osborne JP, Lux AL, Edwards SW, Hancock E, Johnson AL, Kennedy CR, Newton RW, Verity CM, O’Callaghan FJ (2010) The underlying etiology of infantile spasms (West syndrome): information from the United Kingdom Infantile Spasms Study (UKISS) on contemporary causes and their classification.
Approximately one third of children in studies from emergency departments who are evaluated for a ‘‘first’’ seizure will be recognized as having an epilepsy syndrome (Gaillard et al. 2009). Up to one quarter of first seizures occur in the context of genetic (formerly idiopathic) generalized epilepsies, and another one fifth are genetic partial epilepsies, mainly benign rolandic and occipital epilepsies (King et al. 1998). ) (see Figs. 1, 2 in ‘‘What To Do After a First Seizure’’). H. ), MRI in Epilepsy, Medical Radiology.
Since oxy-Hb is more diamagnetic than desoxy-Hb, regional oxy-Hb hyperperfusion leads to subtle magnetic changes which can be identified in serial T2*-weighted images (for review, see Logothetis 2002). uk/spm/) or other techniques, one can statistically evaluate subsequent series of images acquired during the active condition and the control condition. Areas that show changes in magnetic signal temporally associated with the protocol-defined course of the active and the control condition are identified and visualized.